Roger Foo

MD MBBS FRCP FACC FAHA FAMS
Principal Investigator

Roger is a Senior Consultant at the National University Hospital Singapore (NUH) and also a senior investigator at the Cardiovascular Research Institute (NUS) and the Genome Institute of Singapore (GIS). His lab has worked to set up the first Cardiac Genetics clinic in Singapore. Research in the lab remains focussed on making use of genomic technology to discover novel Heart Failure mechanisms.

foosyr@gis.a-star.edu.sg

Albert Dashi

MSc, BSc (Hons)

PhD Student

Albert is a graduate from Switzerland and also has a Masters degree in Biomedical Science obtained at the University of Bern (Switzerland). He has always had a strong interest in microRNA and is currently exploring their role in cardiomyocyte differentiation. His aim is to develop an academic career in the field of cardiovascular translational research.

adashi@gis.a-star.edu.sg

 

Benson Lim

PhD
Post-Doc Fellow

Benson completed his BSc, BSc (Hons) and PhD back-to-back at the University of Melbourne, Australia. He originally trained as a molecular geneticist in the field of plant science and was a post-doc under the supervision of Prof Chris Cobbett working on projects involving Arabidopsis stress-response. He made a switch to mammalian genetics, working on sex-determination genes under the direction of Prof Andrew Sinclair at the Murdoch Childrens Research Institute, Australia, before returning home to Singapore. He joined the Foo-lab in Dec 2015 and now works on the emerging field of circular RNA research.

tsblim@gis.a-star.edu.sg

Cheryl Chan

BSc (Hons)

PhD Student

Cheryl graduated with her B.Sc (2nd Upper Hons) from Singapore’s Nanyang Technological University in 2012 before starting her Ph.D journey in 2014 after earning the A*STAR Graduate Scholarship (AGS, local). Her ideal project was to investigate and understand a subject deeply while acquiring as diverse an array of skills as one possibly could, hence for the past four years, she has been fully immersed in studying a highly novel heterochromatin-associated protein and its functions in a cardiomyocyte. Cheryl always starts her day with coffee and often ends it with some form of exercise (jogging, cycling, training at the gym, or even brisk walking home); and in between, can be found chatting with fellow colleagues, planning her next vacation or thinking about naked mole rats.

chanxlc99@gis.a-star.edu.sg

Chukwuemeka George Onyeka Anene

PhD

Post-Doc Fellow

George is a clinician by training and has worked at the frontline of Nigerian hospitals, treating patients with resources that are vastly more limited than what we are accustomed to Singapore. He has now exchanged stethoscope for pipette, qualifying last year with a NUS PhD in cardiac stem cell bioengineering (at Prof Hanry Yu's lab) and now making further in-roads into cardiovascular epigenetics and epigenomics in our lab. His projects look at DNA damage and cardiac genome enhancer-promoter interactions. A not so secret forte of George's is his multi-lingualism. He speaks fluent Chinese and at least 7 other languages.

mdccgoa@nus.edu.sg

Do Dang Vinh

PhD
Post-Doc Fellow

Vinh is an A*STaR Fellowship award holder. He qualifies with a PhD from NUS from the lab of Fu Xin-Yuan where he worked with Barbara B. Knowles and Davor Solter on STAT signaling pathway. Following a postdoctoral fellowship in the lab of Azim Surani in Cambridge, he is now back in Singapore with a mission to conquer new ground in Cardiovascular Biology. He has a son who is less than a year old and loves spending time with his wife and son when not in the lab. Watching his son grow up is one of his greatest pride and joy in life right now.

dodv@gis.a-star.edu.sg

Dominic Lee

BSc (Hons)

PhD Student

Dom is currently a PhD candidate armed with a major in Genetics from Melbourne University. Interested in finding out how 3D genome architecture affects genes and what makes him and his identical twin brother so different. its probably epigenetics.

dpkslee@gis.a-star.edu.sg

Edita Aliwarga

BSc
Research Assistant

I am a graduate of the Atma Jaya Catholic University in Indonesia with a Bachelor degree in Biotechnology. I started working in the Foo-lab in January 2016 and currently, I am in charge of generating viruses for many in vitro and in vivo projects in our lab. Outside the lab, I like travelling and love to spend time in nature and sometimes I also go swimming after work.

aliwargae@gis.a-star.edu.sg

Eleanor Wong

PhD

Senior Research Fellow

My research interest is in the area of using genomic technologies to profile the epigenome and identify the molecular mechanisms responsible for various cardiovascular cells states in health and disease progression. I am currently investigating the inter-relationship of genetic and epigenetics influences in cardiac hypertrophy which may shed light to the identification of novel therapeutic targets.

I received my PhD in NUS in Dr Ruan Yijun and Dr Wei Chia-Lin's lab at Genome Institute of Singapore.

wonghe@gis.a-star.edu.sg

Ellen Tejo

Dip Biotechnology
Animal Technician

Ellen is our fun loving animal technician. Apart from spending a lot of time shopping and going out with friends, she is a hard-core chocolate lover.

mdcent@nus.edu.sg

Kuan Jyn Ling

BSc (Hons)

Bioinformatics Specialist

Jyn Ling is the other of our lab's computer anorak. She currently works on all of our genomic DNA sequencing projects. These involve annotating our whole genome and whole exome sequencing results, in important collaborative projects with our clinical colleagues including those at KKH, SGH and NUH and overseas. She is also responsible for establishing a genomic database for all the high throughput sequencing projects which our lab is participating in. Jyn Ling is a graduate of the University of Malaya. She has been enjoying a healthy work-life balance with recent holidays to nearby South-East Asian cities.

jlkuan@gis.a-star.edu.sg

Lavenniah Annadoray

BSc (Hons)

PhD student

Lavenniah Annadoray is a graduate from The University of Sydney in 2015 and is now our resident NUS research scholar. She hopes to improve patient’s lives by helping to find a solution for long-term drug delivery, with an innovative technology using circular RNA. Lavi is also an adrenaline junkie, and likes to travel to exotic places in search of activities that allow her to soar in the air. She aims higher every year, be it bungee jumping, dirt bikes or her PhD.

annadorayl@gis.a-star.edu.sg

Lim Choon Kiat

BSc (Hons)

PhD Student

Choon Kiat started working in our lab in Dec 2014 as an A*STAR NGS scholar. His PhD projects aim to understand the changes in epigenetic profiling during transdifferentiation of cardiomyocytes from fibroblasts. He is also studying the dynamics of Lamina-associated Domains (LADs) in chromatin when the the heart is mechanically stretched.

cklim@gis.a-star.edu.sg

Malin Jonsson

PhD

Research Fellow

Malin is an honorary member of the group. She is a PhD graduate from the University of Utrecht and now holds a prestigious EMBO fellowship. Her project works on achieving functional maturity of pluripotent stem cell-derived cardiomyocytes in order to optimize the model as an in vitro tool for studying disease mechanisms and therapies. Malin and her husband re-located to Singapore together in 2013 and their family was recently expanded when their beautiful baby girl was born.

jonssonbm@gis.a-star.edu.sg

Matias Autio

PhD

Senior Research Fellow

Matias’ work in the lab involves developing various stem cell models using CRISPR/Cas9, and other genome engineering tools, as well as studying the 3D & 4D organisation of chromatin. Matias also helps Zenia to manage the activities of the Foo-lab at GIS. He is mentoring four of the PhD students in the group and also assisting a number of other lab members in their projects. In 2016 Matias was awarded the BMRC Young Investigator Grant for CRISPR/Cas9-based high throughput screening for regulators of chromatin organisation.

Matias completed his PhD studies in the Epigenetics and Development lab, in the IRDB at Imperial College, London. Matias is married and outside the lab enjoys board games, Ultimate Frisbee, good beer and watching his son grow up.

autiomi@gis.a-star.edu.sg

Matt Ackers-Johnson

PhD

Post-Doc Fellow

Matt is our lab's microRNA expert. He completed his PhD in Cambridge in Dr Sanjay Sinha's lab on projects involving microRNA and now continues to work in the area as applied to heart failure. He is also working on mapping chromatin changes in heart failure model of laminopathy. When not in the lab on the weekends, Matt can be found partying hard at the Tanjung Beach club in Sentosa. He is nearly never ever seen without a smile, so it is not surprising that Matt is easily our student's most favourite Postdoc Fellow in the lab.

mdcmaa@nus.edu.sg

Mick Lee

BSc

PhD Student

Mick is a NUS PhD Scholar under the Medicine Kwan Im Thong Hood Cho Temple Research Scholarship. Previously working on the Inflammasome signaling pathway, Mick is now aiming to conquer new grounds in cardiovascular research by exploiting a range of molecular tools and unravel how genes behave the way they do under different conditions. Working closely with George, he hopes to understand more about chromatin interactions.
Apart from lab work, Mick is also an avid street photographer and enjoys playing the guitar for leisure.

cjmlee@gis.a-star.edu.sg

Motakis Efthymios

PhD

Post-Doc Fellow

Makis received his PhD in Statistics from the University of Bristol, UK in 2008. Since then he has been mainly working on statistical modelling of gene expression in various labs including the Bioinformatics Institute (Singapore) and Riken Yokohama (Japan). He likes sports, long road trips, photography, art films and classic literature. His favourite quote is "That’s not the point. The point is who will stop me" (The Fountainhead by Ayn Rand). He joined the Foo lab in July 2016 as a senior research fellow to continue his research on single cell transcriptional regulation and dynamics.

mefthymios@gis.a-star.edu.sg

Ning Ding

MSc, BSc (Hons)

PhD Student

Ning is a graduate of the University of York and University of Cambridge. He is now a NUS PhD scholar, working on a project to understand the biology of heterochromatin in the cardiomyocyte. Originally from Shenzhen, China, Ning is also practically a professional singer-performer. He and his wife have a lovely toddler daughter.

nding@gis.a-star.edu.sg

Ng Shi Ling

BSc
Research Assistant

I am a graduate from the University of Western Australia with a Bachelor of Science (Biomedical Science) degree in 2014. Previously I have worked in a clinical histopath lab for 5 years and decided to join the RF research team in 2015. Now I mainly assist the group with histology-related experiments and thus making known as the 'Histo girl'. Apart from work, I enjoy watching Running Man (Korean variety show) and selected Korean drama (those with Lee Min Ho). 

ngsl4@gis.a-star.edu.sg

Oliver Worsley

BSc (Hons)

PhD Student

Oliver is a graduate from the University of Edinburgh and his family lives in Norfolk, UK. Quite surprisingly, Oli looks thoroughly at home in the congested asian metropolis that is Singapore. He is here on a SINGA PhD scholarship, undertaking a systematic study of the epigenetic changes in different physiological and pathophysiological states of the heart. Uncovering driver epigenetic changes may provide clues to novel therapy for heart failure. Recalling his month-long trek across the North Pole, the stresses of a PhD life is a little in comparison.

worsleyo99@gis.a-star.edu.sg

Pan Bangfen

MSc, BSc

Research Associate

Pan Bangfen has a Masters degree in Biochemistry and Molecular Biology and graduated from School of Medicine, Shanghai Jiaotong University, China in June 2014. She ably assists with much of the wet-lab activity at the bench and aims one day to register for PhD studies. She started work in our lab in Aug 2014.

bfpan@gis.a-star.edu.sg

Arnaud PERRIN

Arnaud is a graduate from the Laval University in Canada with a Masters degree in cell and molecular biology, and completed his second Masters degree in gene therapy at the Paul Sabatier University in France.

His research interest deals with genomic technologies, and the CRISPR/Cas9 technology, previously he used them to produce an absent protein in the context of muscular dystrophy disease. Now he is discovering the cardiovascular field while continuing to use the Crispr/cas9 system and other cool stuff !

Arnaud loves to read scientific papers during his hamster is running freely in his apartment, he treasure to chill with beers and friends and enjoys riding his motorcycle when he travels to France. One of his goals with working in Singapore is to travel and visit all the nearby countries around our island, moreover, he is fond of the Asian culture !

perrina@gis.a-star.edu.sg

Peter Li

MSc

CBS Manager

Peter Li is the lab supervisor of operations at NUS while also managing the Comparative Biomedical Services (CBS) within NUS. With almost 10 years of animal research expertise, he manages the in-vivo disease model arm of our lab. He oversees all animal related operations; ranging from management of IACUC protocols, colony cross-breeding, surgery, echocardiography and phenotype assessment.

Peter Li is the lead contact when dealing with collaborators whom require assistance in animal studies; often travelling off-campus both locally and abroad to assist in other operations such as surgery, echocardiogram, breeding strategies and development of animal experiments. He recently graduated with a Masters in Life Sciences (Zoological Sciences) from NTU, continuing his pursue of continuous learning in the field as a zoologist. His two young boys are his other distraction outside of being an animal consultant.

mdcliy@nus.edu.sg

Tuan

Dip Med

Surgeon

Tuan is our group's surgeon. Since starting in our lab in 2013, he has undertaken over 300 operations for our mouse models of heart failure. Not surprisingly, he has more than adequately qualified himself as a reliable pair of hands. Tuan is Vietnamese and has been in singapore since November 2009. He and his wife have 2 sons who are themselves set on the path towards a successful academic future.

mdcldat@nus.edu.sg

Wang Ruifeng

Dip Nursing
Lab Administrator

Ruifeng is our lab administrator and also PA to Roger. She is in charge of lab procurement, clinic appointments and all group finance matters. She joined the lab in early 2015 and enjoys working with this intelligent and passionate team. In her spare time, she swims and practises Chinese calligraphy.

mdcwr@nus.edu.sg

Wilson Tan

BSc (Hons)

Bioinformatics Speciallist

Wilson is one of our lab's computer anoraks. His work on computation, bioinformatics and applied statistics underpins nearly all of our projects. This interprets to mean that he has the heavy responsibility to avoid becoming the bottleneck for our multiple genomic analyses. However Wilson is doing well. Our biologists owe him so many cups of cafe latte that he is guaranteed never to become caffeine-starved for years to come. Wilson is a graduate of the School of Computer Science, NUS. His latest travel was to Kathmandu, roof of the world where he soared across the Tibetian skies to the height of over 1350 metres

wlwtan@gis.a-star.edu.sg

Zenia Tiang

BSc

Lab Manager

Zenia is our sequencing library "constructor extraordinaire". She is the person who links our lab to external collaborators by making RNA and DNA sequencing libraries. One such study (seqCDS, sequencing congenital deformities in singapore) is a collaboration with KKH, singapore's largest maternity and baby hospital. Zenia is also steadily stepping up to a managerial role in our lab, with the all-important mission of cost-efficiency and budgeting. Zenia is a graduate of the School of Science, NUS. In her spare time, she runs, dances and, having visited all of 4 continents, enjoys travelling widely.

ztiang@gis.a-star.edu.sg

Zhao Rong Rong

PhD

Senior Research Fellow

Rongrong is interested in the extracellular matrix (ECM) of heart, in particular the glycogen component of the cardiac ECM. Her work aims to understand the change of ECM during progression of heart failure, and the roles that ECM plays in this process. She is also interested in cardiac fibroblast the main producer of the ECM in particular how do fibroblasts respond to ischemic insult. Before joining the Foo lab, Rongrong studied clinical neuroscience at Cambridge UK. Her work focused on neural plasticity, axon regeneration, and developing treatment for spinal cord injury through ECM modification.Outside the lab, she enjoys travelling, cooking, spending time with friends, and likes to learn and to experience new things.

mdczr@nus.edu.sg

Zhu Yike

BSc

PhD Student

Yike graduated from Zhejiang University in China in the year of 2017 before joining Foo Lab. With a background in pharmacy during her undergraduate study, she is now interested in studying cardiomyocyte proliferation and heart regeneration on mouse models, to eventually promote the drug development in cardiovascular diseases. Outside the lab, Yike loves music and painting. She enjoys playing her favorite zither, learning new musical instruments and sketching. For her, science and art are two things that she wants to pursue forever.

zhu_yike@u.nus.edu

 

Past Members


Dr Ana Vujic (PhD student)

Presently: post-doc fellow at Harvard Stem Cell Institute

Dr Darshan Brahmbhatt (MPhil student)

Presently Cardiology Specialist Registrar, Cambridge

Dr Emma Robinson (PhD student)

Presently: completing PhD studies at Babraham Institute, Cambridge

Dr Kelvin See (Senior Research Fellow)

Presently: Postdoctoral Researcher at Department of Cell and Developmental Biology, University of Pennsylvania

Dr Lina Cordeddu (post-doc fellow)

Presently: post-doc fellow at Karolinska Institutet

Dr Lee Siggens (PhD student)

Presently: post-doc fellow at Karolinska Institutet

Dr Mehregan Movassagh (post-doc fellow)

Presently at Prescient Life Sciences

Suzanne Tan (Research Assistant)

BSc
Presently in Spain

Chua Wee Woon (Laboratory Technologist)

BSc
Presently: Medical Technologist in Angsana Molecular and Diagnostics Laboratory.

Everett (Research Assistant)

BSc (hons.)
Presently: PhD Student in GIS

 

Interns (past & present)

 

Brett Joseph COLLINGE (University of British Columbia)

SIPGA scholar

Priscilla Lim Xin Yi (National University of Singapore)

Final Year Honours student

Seow Wei Qiang (NUS, Singapore)

Presently, A*STaR PhD scholar at University of Cambridge

Lam Shing Pheng (Ngee Ann Polytechnic)

Phillina Yihui Phua (Ngee Ann Polytechnic)

Presently, NUS School of Science

Chunjie Wong (Hwa Chong Institution)

Presently NTU Medical School

Yee Shiun Chan (NUS High School)

Benjamin Lee (NTU Medical School)

Daobo Wang (NUS Medical School)

Sia Tze Yang (Raffles Institution)

Presently NUS Medical School

Tan Ting Fang (Raffles Institution)

Presently NUS Medical School

Raphael Soh (Raffles Institution)

Presently NUS Medical School

Kritchai “Jay” Vutipongsatorn (Temasek JC)

Presently, Imperial College London Medical School

Li Ting Lee (Temasek Polytechnic)

Presently, NTU School of Science

Irwin Ng (Republic Polytechnic)

Melvin Yong (Republic Polytechnic)

Ellen Tejo (Republic Polytechnic)

Jade Tangqi Ng (Murdoch University)

Valencia (NTU School of Science)

Nicole Yuk Yin Choi (Ngee Ann Polytechnic)

Presently, NUS Medical School

Ser Ning Poh (Ngee Ann Polytechnic)

Jing Han Ng (NUS Medical School)

Yi Hao Nah (Republic Polytechnic)

Robin Hartman (University of Utrecht)

Ahmad Salehi (Iran University)

Tan Yong Hong (NUS Medical School)