MPhil, PhD (Cantab)
BSc (1st Class Hons, Newcastle)
Senior Research Fellow
Lee is British and did his undergraduate degree in Food and Human Nutrition at Newcastle University. He then moved to Cambridge University and enrolled in a Welcome Trust 4-year MPhil/PhD scholarship at the Institute of Metabolic Science and Department of Medicine (Cardiovascular division). He then moved to Stockholm for his postdoctoral research at the Karolinska Institute. He is interested in epigenomics and recently joined the Foo-lab at NUS and Genome Institute of Singapore.
MPhil and PhD, Institute of Metabolic Science and Department of Medicine, University of Cambridge
BSc (1st Class Hons) Food and Human Nutrition, Newcastle University
- Jurisic A, Robin C, Tarlykov P, Siggens L, Schoell B, Jauch A, Ekwall K, Sørensen CS, Lipinski M, Shoaib M, Ogryzko V. Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains. Nucleic Acids Res. 2018 Dec 14;46(22):e135.
- Zaghloul EM, Gissberg O, Moreno PMD, Siggens L, Hällbrink M, Jørgensen AS, Ekwall K, Zain R, Wengel J, Lundin KE, Smith CIE. CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression. Nucleic Acids Res. 2017 May 19;45(9):5153-5169.
- Qu Y, Siggens L, Cordeddu L, Gaidzik VI, Karlsson K, Bullinger L, Döhner K, Ekwall K, Lehmann S, Lennartsson A. Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia. Blood. 2017 Feb 16;129(7):e13-e25.
- Sadeghi L*, Siggens L*, Svensson JP, Ekwall K. Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity. Nat Struct Mol Biol. 2014 Mar;21(3):236-43.